// Area 01 — Diagnostics

Assays that
hold up in the field.

Assay and reagent development for molecular and immunoassay diagnostics — including antigen and antibody design, binder optimisation and assay-grade protein supply for research and clinical laboratories.

Formats
Molecular · Immunoassay
We design
Antigens, antibodies, binders
We supply
Assay-grade proteins & reagents
Typical partner
Research & clinical laboratories

// Diagnostics

Specificity is a protein problem.

Most assay failures trace back to the binder, not the instrument.

An antibody engaging an antigen

A diagnostic is only as good as the molecules inside it. Cross-reactivity, drift between lots, signal that collapses at the low end — these usually come back to an antigen or an antibody that was good enough to publish and not good enough to ship.

We work on that layer. Structure-guided design and in-silico screening narrow a candidate set before anything reaches a bench, and the laboratory result feeds back into the next design round.

Where we come in

  • Antigen and antibody design for a defined target, including epitope selection.
  • Binder optimisation — affinity, specificity and off-target behaviour.
  • Expression strategy so a reagent can actually be made at the volume you need.
  • Stability work for the storage and shipping conditions the assay will really see.
  • Assay-grade protein supply once the design is settled.

Formats we work in

Molecular diagnostics including PCR-based workflows, and immunoassay formats including ELISA and lateral flow. In vitro diagnostics for both research use and clinical laboratory settings.

// Capability

What we
actually do.

The specific pieces of work an engagement in this area is made of.

  • 01

    Target & epitope selection

    Deciding what the assay should actually see, and which surface to raise a binder against.

  • 02

    Computational binder design

    Structure-guided and sequence-based design, ranked in silico before synthesis.

  • 03

    Specificity engineering

    Reducing cross-reactivity against the panel the assay will meet in practice.

  • 04

    Expression & yield

    Construct and host strategy so the reagent is manufacturable, not just demonstrable.

  • 05

    Stability & shelf life

    Formulation and sequence-level work for real storage and transport conditions.

  • 06

    Supply

    Assay-grade proteins, reagents, kits and consumables with documented provenance.

// Questions

Asked
often.

If yours is not here, ask it directly — every enquiry is read by someone who can answer it.

  • We already have a working assay. What would you change?

    Usually nothing about the assay — we look at the binder. If lot-to-lot variation, cross-reactivity or low-end sensitivity is the complaint, the protein is the first place to look.

  • Do you supply reagents without a design engagement?

    Yes. Assay-grade proteins, reagents, culture media, consumables and instrumentation can be supplied on their own to research and clinical laboratories in the region.

  • Can you work under our NDA?

    Yes, and we will sign it before a technical discussion if you prefer.